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Vitamin C Study Question For The Dr.

 
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lancebr



Joined: 16 Mar 2006
Posts: 13

PostPosted: Mon Nov 24, 2008 8:15 pm    Post subject: Vitamin C Study Question For The Dr. Reply with quote

Hello Dr.:

The study link below was recently brought to my attention which basically says that Vitamin C does increase the production of collagen, but at the same time also decreases the production of elastin.

jbc.org/cgi/content/abstract/272/1/345


What is your opinion on this? Can vitamin C possibly decrease the production of elastin?



Thanks

LB
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drtodorov
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Joined: 10 Dec 2004
Posts: 3083

PostPosted: Tue Nov 25, 2008 9:48 pm    Post subject: Reply with quote

This is an interesting article but without human clinical studies of the effects of common topical vitamin C formulations on elastin synthesis, it is hard to say how relevant this data is. On the other hand, topical C has been clinically shown to improve fine lines and wrinkles. There is no need to use topical C all of the time, just do periodic courses, so, even it depresses the production of elastin, you'll give elastin levels time to recover.

That said, elastin is important and steps to boost it make sense regardless of whether you are periodically using topical C or not.

See smartskincare.com/skinbiology/skinbiology_elastin.html
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kim_berlyski



Joined: 26 Nov 2008
Posts: 1

PostPosted: Wed Nov 26, 2008 8:25 am    Post subject: Vitimin C Stability Reply with quote

Maybe you can help me with my question. Recently at a spa I was informed about Vitamin C, and how it is very good for aging skin.
The derm also told me that "Unfortunately, Vitamin C is very unstable. If exposed to oxygen, it oxidizes becomes almost ineffective." They showed me one prduct (c-vit) that supposedly is "stabilized" with something preventing it from oxidizing.
The problem is it is a bit expensive.

I am wondering is this true? does vitamin c really oxidize? Can it be stabilized? and is it still good for your skin after stabelized?

Thanks a bunch
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drtodorov
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Joined: 10 Dec 2004
Posts: 3083

PostPosted: Wed Nov 26, 2008 8:59 am    Post subject: Reply with quote

Yes, it does oxidize but there are affordable ways to deal with it, including DIY approach. See my articles on vitamin C, its formulations and its derivatives here smartskincare.com/treatments/topical/
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suzq



Joined: 05 Jun 2008
Posts: 6
Location: CHICAGO

PostPosted: Wed Nov 26, 2008 12:33 pm    Post subject: Reply with quote

I have heard alot of good things about Vitamin C Serum from E Burnham Co. You have to get it from the website.
SQ
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jands



Joined: 21 Nov 2005
Posts: 104
Location: Taiwan

PostPosted: Wed Nov 26, 2008 10:01 pm    Post subject: Reply with quote

They do not list the ingredients on their website, so there is no way to find out what makes it 'better' than other C formulations.
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tanya_yakobo



Joined: 24 Apr 2008
Posts: 2

PostPosted: Thu Nov 27, 2008 6:14 am    Post subject: C-vit Reply with quote

Kimberly, C-vit is actually not a product but a product line, and it is very effective. In comparasion to some of the other "stabelized" vitamin c from other companies, it is moderatley priced.

I did want to commet on the coment made by jands. Im not sure what product you were refering to, but in all c-vit products, all ingredients are listed, atleast on the manufacture website anyway (sesderma).
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Virgo



Joined: 11 Aug 2006
Posts: 192

PostPosted: Mon Dec 01, 2008 3:31 pm    Post subject: Reply with quote

I've been wondering about the benifits of topical Grape Seed extract vs. a Vit. C form, like MAP.

I know that both MAP and Grape Seed are good antioxidants, but does MAP do more for your skin in other ways than Grape Seed? Or, if in fact, Vit. C does inhibit elastin, might Grape Seed be the better choice?

I doubt that there are any side-by-side sudies, but I would be very interested in hearing Dr. Todorov's opinion?
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drtodorov
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Joined: 10 Dec 2004
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PostPosted: Mon Dec 01, 2008 6:30 pm    Post subject: Reply with quote

At this point, the inhibition of elastin by C in "real life" is a speculation, where vit C it is proven to stimulate collagen, which grape seed extract does not.
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Valie



Joined: 05 Dec 2008
Posts: 4

PostPosted: Fri Dec 05, 2008 10:18 am    Post subject: Reply with quote

Can you tell me if there is a difference between Ascorbic acid and L-ascorbic acid? I read that L-ascorbic acid is the best form of vit.c you can use.

I noticed that almost all vit.C powders are packed in clear, plastic bags. Can vitamin C oxidize when it is still in a powder form or it begins to oxidize whe we mix it with other ingredients?
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drtodorov
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Joined: 10 Dec 2004
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PostPosted: Fri Dec 05, 2008 10:23 am    Post subject: Reply with quote

Formally, ascrobic acid is a mix of two forms (optical isomers) D and L. However, sometimes people imprecisely say or write "ascrobic acid" when refrerring to just L-ascorbic acid, which is vitmain C.

There would be some relatively slow oxidation of dry C powder exposed to sunlight and air. However, oxidation is much faster if there is water present.
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drtodorov
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Joined: 10 Dec 2004
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PostPosted: Fri Dec 05, 2008 10:24 am    Post subject: Reply with quote

Formally, ascorbic acid is a mix of two forms (optical isomers) D and L. However, sometimes people imprecisely say or write "ascorbic acid" when referring to just L-ascorbic acid, which is vitamin C.

There would be some relatively slow oxidation of dry C powder exposed to sunlight and air. However, oxidation is much faster if there is water present.
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mills



Joined: 09 Nov 2007
Posts: 16

PostPosted: Wed Dec 24, 2008 6:34 pm    Post subject: Reply with quote

dr .t when you say perodically use topical c . how many times a week?
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drtodorov
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Joined: 10 Dec 2004
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PostPosted: Wed Dec 24, 2008 7:40 pm    Post subject: Reply with quote

By "periodically", I mean using it for a few weeks (e.g. 6-8 weeks), then makes a break for a few weeks or even months; then repeat.
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jamie555



Joined: 28 Dec 2008
Posts: 19

PostPosted: Mon Jan 05, 2009 2:36 am    Post subject: Reply with quote

drtodorov wrote:
By "periodically", I mean using it for a few weeks (e.g. 6-8 weeks), then makes a break for a few weeks or even months; then repeat.


I agree. I follow nearly that exact regime, and the results have been great for me over the long term. Also get a smooth brighter complexion.
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