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Spherical Nucleic Acids as new class of actives?

 
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citrine



Joined: 19 Mar 2007
Posts: 4

PostPosted: Fri Apr 24, 2015 7:29 am    Post subject: Spherical Nucleic Acids as new class of actives? Reply with quote

Stumbled on to this:

sciencedaily.com/releases/2015/04/150423102621.htm
Nanotech-enabled moisturizer speeds healing of diabetic skin wounds

Quote:
Scientist and dermatologist Amy S. Paller and chemist Chad A. Mirkin are the first to develop a topical gene regulation technology that speeds the healing of ulcers in diabetic animals. They combined spherical nucleic acids (SNAs, which are nanoscale globular forms of RNA) with a common commercial moisturizer to create a way to topically knock down a gene known to interfere with wound healing.


Wonder what other genes they could target?
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drtodorov
Site Admin


Joined: 10 Dec 2004
Posts: 3177

PostPosted: Sat Apr 25, 2015 7:54 pm    Post subject: Reply with quote

On could think of a number of potential targets, e.g. telomerase, melanin synthase, glutathione synthase, etc.
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