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Copper Peptides and Tetrahexyldecyl Ascorbate (vit C) ?

 
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orangehrzn



Joined: 23 Feb 2005
Posts: 1005

PostPosted: Sun Jan 15, 2006 12:14 pm    Post subject: Copper Peptides and Tetrahexyldecyl Ascorbate (vit C) ? Reply with quote

I know CP are not compatible with the usual acidic forms of vit. C. Is that also true for non-acidic forms like Tetrahexyldecyl Ascorbate?
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Sun Jan 15, 2006 5:46 pm    Post subject: Reply with quote

I can't tell you for certain without actually running studies but there is a chance that any ascorbate may enhancedamaging effects of copper. See article below. It does not mean that the same happens in the skin, but this is a good enough reason to avoid mixing any ascorbates and copper at this point.

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Int J Biochem. 1984;16(2):155-9.

Ascorbate (vitamin C) and dehydroascorbate stimulation of copper induced hemolysis. Protective action of ceruloplasmin, albumin and apotransferrin.

Lovstad RA.

Copper ion induced lysis of rat erythrocytes was markedly stimulated by low concentrations of ascorbate and dehydroascorbate. Ascorbate oxidase, superoxide dismutase, catalase or scavengers of hydroxyl radicals protected erythrocytes against copper-ascorbate stimulated lysis. It is proposed that superoxide radicals and hydrogen peroxide cooperate in producing hydroxyl radicals, which are directly involved in hemolysis. The serum proteins, ceruloplasmin, albumin and apotransferrin, also reduced the hemolytic action of copper-ascorbate, the order of effectiveness being; ceruloplasmin greater than albumin greater than apotransferrin.
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