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r Lipoic Acid
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newdawn



Joined: 05 Apr 2006
Posts: 2

PostPosted: Wed Apr 05, 2006 10:54 pm    Post subject: r Lipoic Acid Reply with quote

I followed instructions for making DIY DMAE & R-Lipoic Acid Cream. The R-Lipoic Acid I got was from lef.com and is called R-Dihydro-Lipoic Acid. It is in a capsule and is kind of this oily stuff. They said it was encapsulated because it cannot be exposed to air. Well I mixed the cream together and had no trouble but am wondering if, since the RLA has now been exposed to air if I am making a mistake by using this kind of RLA. Also, it doesn't smell too good either. Opinions?
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Thu Apr 06, 2006 3:41 am    Post subject: Reply with quote

R-Dihydro-Lipoic Acid is not the same as R-Lipoic Acid. R-Dihydro-Lipoic Acid oxidizes too easily and is not suitable for topical use.
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yogagirl



Joined: 13 May 2005
Posts: 84

PostPosted: Thu Apr 06, 2006 5:52 am    Post subject: Reply with quote

Dr. T - I read on another skin care forum that alpha lipoic acid should not be used by people with acne, as it can make it worse. But Dr. Perricone suggests it in his acne cure book. What is your opinion about this. Can it make breakouts worse, or does it help heal acne?
Thanks!
:D
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newdawn



Joined: 05 Apr 2006
Posts: 2

PostPosted: Thu Apr 06, 2006 11:17 am    Post subject: thanks for response Reply with quote

Thank you so much for your quick reply. You have saved me from a screwup. This was my first attempt at DIY so I'll go back and start over. I love the DIY info you supplied. It is empowering that I can make my own rather than get ripped off by cosmetic companies. Thanks!
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Thu Apr 06, 2006 12:11 pm    Post subject: Reply with quote

I haven't seen any data as to ALA improving or worsening acne. But some people with acne find a wide range of topicals comedogenic.
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Mike



Joined: 29 Sep 2006
Posts: 121

PostPosted: Thu Oct 19, 2006 12:16 am    Post subject: r-Lipoic Acid topical Reply with quote

Does anybody know of any topical preparation that contains r-alpha lipoic acid rather than the mix of R & L alpha lipoic acid? If there were such a product, would the r-alpha lipoic acid have to be stabalized with Sodium or Potassium to be of any use?
Thanks!
Mike
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Thu Oct 19, 2006 12:23 am    Post subject: Reply with quote

Sodium or potassium salts are used mainly to prevent R-ALA powder to form insoluble clumps during storage. If R-ALA is dissolved in a vehicle, it can be used as is, just like racemic (regular) ALA.
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pinkconga



Joined: 19 Jan 2006
Posts: 12

PostPosted: Thu Oct 19, 2006 5:12 pm    Post subject: Reply with quote

Try gardenofwisdom.com for r-ala or psfskincare.com
They both have a 3% r-ala
maybe bulkactives has too and check lotioncrafter
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Mike



Joined: 29 Sep 2006
Posts: 121

PostPosted: Sat Oct 21, 2006 10:14 pm    Post subject: Reply with quote

Can stabilized R-Lipoic acid be bought in any form that can be used by a DIY to make a topical prepartion? If so, what would make sense to use as the base vehicle?
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PattiK



Joined: 09 Jan 2006
Posts: 11

PostPosted: Mon Oct 23, 2006 2:33 pm    Post subject: Reply with quote

GeroNova makes a number of different R-ALA products. They have a liquid R-ALA. They also have a ton of information on R-ALA.

www.geronova.com
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Mon Oct 23, 2006 3:09 pm    Post subject: Reply with quote

There R-ALA gel has 50% R-dihydro-ALA, which is too easlity oxidised and likely not appropriate for topical use.
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Mike



Joined: 29 Sep 2006
Posts: 121

PostPosted: Mon Oct 23, 2006 4:27 pm    Post subject: Reply with quote

How about this product from zlabs for making a topical R-Lipoic Acid ?

http://www.zlabs.us/rala.html
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Mon Oct 23, 2006 7:44 pm    Post subject: Reply with quote

That one is R-ALA powder not solubilized R-ALA, as far as I can see. It can be used but I thought the question was where to find solubilized R-ALA as to avoid the need to solubilize it yourself.
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Mike



Joined: 29 Sep 2006
Posts: 121

PostPosted: Mon Oct 23, 2006 7:47 pm    Post subject: Reply with quote

Can you recommend a base that would be appropriate for this product?
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Mike



Joined: 29 Sep 2006
Posts: 121

PostPosted: Tue Nov 14, 2006 2:00 am    Post subject: Reply with quote

Would this be a better choice for a DIY R-ALA topical?

http://www.geronova.com/Merchant2/merchant.mvc?Screen=CTGY&Store_Code=GS&Category_Code=KR10

Thanks!

Mike
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