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r Lipoic Acid
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drtodorov
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Joined: 10 Dec 2004
Posts: 3177

PostPosted: Tue Nov 14, 2006 2:15 am    Post subject: Reply with quote

Possibly. However, potassium salt probably does not penetrate skin as well as lipoic acid, so ideally one whould want to make sure that when you mix this with a vehicle, you get close to neutral pH, in which case most of lipoic acid will be in neutral form. Many vehicles have enough buffering capacity to remain neutral even when mixed with somewhat alkaline salt like K-ALA.
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Mike



Joined: 29 Sep 2006
Posts: 121

PostPosted: Sun Nov 19, 2006 2:50 pm    Post subject: Reply with quote

If I can find a Sodium Salt (Na) of R-Lipoic acid, that came in a liquid form, would that be better than the Potassium Salt of R-Lipoic Acid as far as penetration is concerned?
Thanks!
Mike
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drtodorov
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Joined: 10 Dec 2004
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PostPosted: Sun Nov 19, 2006 3:37 pm    Post subject: Reply with quote

Hard so say - lipoic acid penetrates better since it is not charged, but the salt might be a bit more stable. However, if a vehicle you use has some buffering capacity, it wouldn't even matter in what you add. The dissociation state of lipoic acid in solution depends on pH, not so much on whether you initially added lipoic acid salt or lipoic acid itself.
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ChadG



Joined: 16 Jul 2008
Posts: 1

PostPosted: Wed Jul 16, 2008 12:27 pm    Post subject: Reply with quote

Here's another R ALA to consider. It has 75 mg R ALA, 75 mg R dihydrolipoic acid, and 50 mg CoEnzyme Q10.

Check it out, they have a pretty resourceful sight about R ALA and all its benefits:

Ralapure.com/
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drtodorov
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PostPosted: Wed Jul 16, 2008 7:26 pm    Post subject: Reply with quote

dihydrolipoic acid oxidises too easily. it is likely not a good idea to use it topically
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