Skin aging: postulated mechanisms and consequent changes in structure and function.

Author: Yaar M, Gilchrest BA

Author affiliation: Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

Publication date & source: 2001.11, Clin Geriatr Med., 17(4):617-30, v.

Publication type: Review; Review, Tutorial

Aging is a complex process influenced by telomere shortening and damage to cellular DNA. New insights into age-associated decrements in DNA damage repair are reviewed. Age-associated gross, histologic, and functional cutaneous deficits are delineated. Different treatment options for aged skin are examined.

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