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You are here: Skin Care Research >

Localized granulomatous reaction to a semi-permanent hyaluronic acid and acrylic hydrogel cosmetic filler.

Author: Sidwell RU, Dhillon AP, Butler PE, Rustin MH

Author affiliation: Department of Dermatology, Royal Free Hospital, London, UK.

Publication date & source: 2004.11, Clin Exp Dermatol., 29(6):630-2.

Publication type: Case Reports

Dermalive, an injectable skin filler composed of a combination of synthetic hyaluronic acid and acrylic hydrogel particles was recently developed for soft tissue augmentation. Dermalive produces longer term results than temporary injectable fillers and is associated with a reportedly low incidence of adverse reactions. We describe a marked local reaction to the injection of Dermalive in the nasolabial fold developing within 4 months with histological confirmation of a granulomatous response. To our knowledge there has been only one previous report of a local granulomatous reaction to Dermalive.



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