Subsurface skin renewal by treatment with a 1450-nm laser in combination with dynamic cooling.

Author: Paithankar DY, Clifford JM, Saleh BA, Ross EV, Hardaway CA, Barnette D

Author affiliation: Candela Corporation, 530 Boston Post Road, Wayland, Massachusetts 01778, USA. dilip.paithankar@clzr1.com

Publication date & source: 2003.07, J Biomed Opt., 8(3):545-51.

Publication type: Clinical Trial; Clinical Trial, Phase I; Clinical Trial, Phase II; Randomized Controlled Trial

A new nonablative laser device, Smoothbeam, has been under evaluation for nonablative wrinkle reduction in skin with minimal side effects. This device incorporates a laser at 1450-nm wavelength to heat the dermis and cryogen spray cooling to prevent epidermal damage. The thermal injury created is internal and imperceptible. The wound-healing response to this internal injury causes improvement in the appearance of skin wrinkles. Biopsies taken immediately after treatment showed mild residual thermal damage (RTD) at a depth range of 150 to 400 microm, which is the dermal zone where most solar elastosis resides. Biopsies from two months after treatment showed fibroplasia extending over a range of depths similar to the acute RTD zones. An improvement in wrinkle severity was noted on the treated side compared with the control side. (c) 2003 Society of Photo-Optical Instrumentation Engineers.

Indexes of Skin Care Research Abstracts by Subject Category Most Recent

Web SmartSkinCare.com

Home | About Us | Contact Us | Ask a Question | Resources

Copyright © 1999-2008 by Dr. G. Todorov / SmartSkinCare.com
Site Disclaimer | Copyright Certification