The use of fluor-hydroxy pulse peel in actinic porokeratosis.

Author: Teixeira SP, de Nascimento MM, Bagatin E, Hassun KM, Talarico S, Michalany N

Author affiliation: Department of Dermatologym Cosmiatry Division, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Brazil. solangeteixeira@clinderm.com.br

Publication date & source: 2005.09, Dermatol Surg., 31(9 Pt 1):1145-8.

Publication type: Case Reports

BACKGROUND: The use of Fluor-Hydroxy pulse peel (Drogaderma, Sao Paulo, Brazil) was reported by Katz to treat solar damage and actinic keratosis-associated lesions. OBJECTIVE: The objective was to use this combined treatment to produce therapeutic and cosmetic benefits in a patient with actinic porokeratosis. METHODS: A case of actinic disseminated porokeratosis was treated with a combination of a 70% glycolic peel and a 5% 5-fluorouracil solution (Drogaderma) every 2 weeks for 4 months. A biopsy was done before and after eight treatment pulses. Results: Improvement in the appearance and texture of the treated areas and decreased dyskeratosis and epidermal atypia. CONCLUSION: The Fluor-Hydroxy pulse peel can be an effective alternative for the treatment of actinic porokeratosis.

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