 |
| Intelligent anti-aging skin care based on independent research |
| Lose wrinkles, keep your bank account! |
|
|
|
|
 |
You are here: Skin Care Research >
Author: Kang S, Krueger GG, Tanghetti EA, Lew-Kaya D, Sefton J, Walker PS, Gibson JR, Tazarotene Cream in Photodamage Study Group
Author affiliation: University of Michigan Medical Center, Department of Dermatology, Ann Arbor, Michigan 48109-0314, USA. swkang@med.umich.edu
Publication date & source: 2005.02, J Am Acad Dermatol., 52(2):268-74.
Publication type: Clinical Trial; Multicenter Study; Randomized Controlled Trial
BACKGROUND: Previous studies indicate that tazarotene is efficacious in reducing signs of photodamage. Objective We sought to confirm the efficacy and tolerability of tazarotene 0.1% cream in the treatment of facial photodamage. METHODS: A total of 568 patients with at least moderate fine wrinkling or mottled hyperpigmentation applied tazarotene 0.1% cream or vehicle cream to their face once daily for 24 weeks. RESULTS: Tazarotene cream was significantly more effective than vehicle in reducing fine wrinkles, mottled hyperpigmentation, lentigines, irregular depigmentation, apparent pore size, elastosis, tactile roughness, and an overall integrated assessment of photodamage. Significance was achieved as early as week 2 for some parameters and had not plateaued by week 24. The majority of patients reported improvements in their photodamage as early as week 4. Adverse events were predominantly mild or moderate signs or symptoms of skin irritation. CONCLUSION: Once-daily tazarotene 0.1% cream is effective in ameliorating multiple signs of facial photodamage.
Home | About Us | Contact Us | Ask a Question | Resources Copyright © 1999-2009 by Dr. G. Todorov / SmartSkinCare.com Site Disclaimer | Copyright Certification
|
|
|||||||||||||||||||||||||||||||||||||||||||||||||