Azelaic acid (15% gel) in the treatment of acne rosacea.

Author: Gupta AK, Gover MD

Author affiliation: Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Sciences Center, University of Toronto, Toronto, Ontario, Canada. gupta@execulink.com

Publication date & source: 2007.05, Int J Dermatol., 46(5):533-8.

Publication type: Research Support, Non-U.S. Gov't; Review

In December of 2002, the FDA approved azelaic acid 15% gel for the topical treatment of inflammatory papules and pustules of mild to moderate rosacea. Azelaic acid is a saturated dicarboxylic acid, which is naturally occurring and has been used in the treatment of rosacea, acne, and melasma. The 15% gel has a high efficacy and is generally well tolerated, with the local irritation (burning, stinging, itching, and scaling) being typically mild and transient. Azelaic acid 15% gel is considered effective and safe as a therapy for inflammatory papulo-pustular rosacea and is suitable for use on all skin types.

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