Safety and efficacy comparison of blue versus red light sources for photodynamic therapy using methyl aminolevulinate in photodamaged skin. [2011.01]
Background and Objective: Methyl aminolevulinate (MAL) is a recently FDA-approved molecule for photodynamic therapy (PDT) in the treatment of nonhyperkeratotic actinic keratoses (AK). In the U.S., aminolevulinic acid (ALA) has been used in an off-label manner with photodynamic therapy for the treatment of chronic photodamage...
Vitiligo following intense pulsed light treatment. [2010.07]
Vitiligo is an acquired depigmenting disorder characterized by the progressive loss of melanocytes from the epidermis and epidermal appendages, which results in milky-white macular lesions... Therefore, dermatologists should be aware of unsighted vitiligo lesion before IPL treatment.
Intense pulsed light vs. pulsed-dye laser in the treatment of facial acne: a randomized split-face trial. [2009.12.11]
Background Various laser and light therapy have been increasingly used for the treatment of acne vulgaris. Patients and methods Twenty patients with facial acne were treated using intense pulsed light (IPL) on one side of the face and pulsed dye laser (PDL) on the other to compare the efficacy and safety of IPL and PDL...
Topical antioxidant application augments the effects of intense pulsed light therapy. [2009.12]
BACKGROUND: There has been great interest in improving the efficacy of nonablative technologies by combining them during facial skin rejuvenation. The purpose of this study was to determine whether the addition of topical polyphenolic antioxidants to an intense pulsed light (IPL) treatment regimen augmented the effects of facial IPL treatments... CONCLUSION: The addition of polyphenolic antioxidants to an IPL regimen improved the clinical, biochemical, and histological changes seen following IPL treatment alone. These data support the use of multimodal therapy to create synergy and to optimize clinical outcomes in nonablative facial skin rejuvenation.
A comparative study of topical 5-aminolevulinic acid incubation times in photodynamic therapy with intense pulsed light for the treatment of inflammatory acne. [2009.12]
CONCLUSION: PDT with a long ALA incubation time might be more adequate for a pronounced outcome with inflammatory acne.
Topical polyphenolic antioxidants reduce the adverse effects of intense pulsed light therapy. [2009.09]
BACKGROUND: Intense pulsed light therapy (IPL) has been associated with erythema and increased lipid peroxidation. Polyphenolic antioxidants have been shown to decrease inflammation and reduce oxidative stress in irradiated skin. Objective: To determine whether the topical application of polyphenolic antioxidants to IPL-treated skin reduced the adverse effects of IPL exposure... CONCLUSIONS: In this study, the concurrent pneumatic topical application of polyphenolic antioxidants reduced lipid peroxidation and skin dehydration in IPL-treated skin. Polyphenolic antioxidants may confer a protective effect on facial skin and enhance the effects of IPL therapy.
Benefits of using a hydroquinone/tretinoin skin care system in patients undergoing intense pulsed light therapy for photorejuvenation: a placebo-controlled study. [2009.09]
A hydroquinone/tretinoin (HQ/tret) skin care system designed for use with non-surgical facial rejuvenation procedures has recently become available. In this observer-masked study, 36 patients with moderate-to-severe wrinkling of the skin around the eyes and lips were randomly assigned to use either the 4% hydroquinone/0.05% tretinoin skin care system or placebo products, each day for 90 days...
Assessment of the optical radiation hazard from a home-use intense pulsed light (IPL) source. [2009.09]
BACKGROUND AND OBJECTIVES: Intense pulsed light (IPL) systems have evolved and crossed over from the clinic to the home. Studies have shown home-use IPLs to be clinically effective but there has been no published data on ocular safety. It was our aim to measure the spectral and temporal optical radiation output from a home-use IPL and assess the ocular hazard... CONCLUSIONS: The home-use device that we assessed does not present an optical hazard according to currently available international standards.
Hair removal with a novel, low fluence, home-use intense pulsed light device. [2009.06]
OBJECTIVE: To evaluate the reduction in unwanted body and facial hair at various body sites of Fitzpatrick skin types I-III and the efficacy, comfort and safety of this treatment intended for home-use by the general public... CONCLUSIONS: In simulated consumer use, this home-use IPL demonstrated a significant, quantifiable and sustainable reduction in unwanted body and facial hair with minimal side effects.
Treatment of facial port-wine stains with intense pulsed light: a prospective study. [2008.06]
CONCLUSION: Moderate effectiveness was achieved with IPL treatment in the facial port-wine stains.
Split-face comparison of the erbium micropeel with intense pulsed light. [2008.06]
BACKGROUND: A variety of photorejuvenative techniques have been utilized to reverse the signs of cutaneous photoaging, including ablative and nonablative laser resurfacing as well as light-based devices. OBJECTIVE: The purpose of this split-face randomized prospective open-label trial was to determine the effectiveness of sequential erbium:yttrium-aluminum-garnet (Er:YAG) laser versus intense pulsed light (IPL) for the treatment of mild to moderate facial photodamage... CONCLUSIONS: While low-fluence erbium resurfacing has a modest effect on facial photodamage, patients preferred IPL because it resulted in less downtime. The authors have indicated no significant interest with commercial supporters.
Use of light-emitting diode photomodulation to reduce erythema and discomfort after intense pulsed light treatment of photodamage. [2008.03]
OBJECTIVES: This study evaluates the use of light-emitting diode (LED) photomodulation therapy to accelerate resolution of post-intense pulsed light (IPL) erythema... CONCLUSION: LED photomodulation treatment may accelerate the resolution of erythema and reduce posttreatment discomfort in IPL-treated patients with photodamage.
Effect of a new infrared light device (1100-1800 nm) on facial lifting. [2008.02]
Laser skin resurfacing procedures can be classed into two categories - invasive and non-invasive. The last several decades have witnessed a host of advancements in ablative laser therapy and other ablative modalities for the rejuvenation of skin, including the CO(2) laser, the erbium : yttrium aluminum garnet laser, chemical peels, and dermabrasion.
Intense pulsed light versus advanced fluorescent technology pulsed light for photodamaged skin: a split-face pilot comparison. [2007.10]
Intense pulsed light (IPL) has been a popular nonablative treatment of photodamage. A prospective, randomized, controlled, single-blinded, split-face pilot study compared the efficacy and safety of 2 multitechnology broadband pulsed light platform devices: an IPL device (Lumenis One, Lumenis Corporation, Santa Clara, CA) and a fluorescent pulsed light with advanced fluorescent technology (AFT, Harmony System, Alma Lasers, Buffalo Grove, IL) device...
Acne and PDT: new techniques with lasers and light sources. [2007.06]
Acne vulgaris is one of the most common dermatologic disorders encountered in everyday practice.More and more clinical trials are showing the effectiveness of 5-aminolevulinic acid and photodynamic therapy in the treatment of moderate to severe inflammatory acne vulgaris.
Photodynamic therapy with lasers and intense pulsed light. [2007.05]
For many physicians, photodynamic therapy has become a routine part of using lasers and light sources to improve the outcomes of photorejuvenation therapies. Aminolevulinic acid photodynamic therapy (ALA-PDT) was first used in the treatment of actinic keratoses in the United States... This article reviews the peer-reviewed literature regarding ALA-PDT in photorejuvenation and also summarizes the author's own techniques in using this new and exciting therapeutic method.
Objective evaluation of the effect of intense pulsed light on rosacea and solar lentigines by spectrophotometric analysis of skin color. [2007.04]
BACKGROUND: To date, intense pulsed light (IPL) has been applied to various skin diseases, but there have been few objective evaluations of its efficacy. OBJECTIVE: The aim of this study was to perform objective evaluations of the effect of the IPL system on rosacea and solar lentigines... CONCLUSION: As demonstrated by spectrophotometric analysis of skin color, IPL at the wavelength of 550 to 670 nm is effective for rosacea and solar lentigines, particularly most useful for erythematotelangiectatic rosacea.
Intense pulsed light therapy for superficial pigmented lesions evaluated by reflectance-mode confocal microscopy and optical coherence tomography. [2006.10]
Intense pulsed light (IPL) therapy is reported to be effective for pigment removal from pigmented lesions. However, the dynamic mechanism of pigment removal by IPL therapy is not completely understood... However, additional application of suppressive drugs such as hydroquinone or Q-switched laser irradiation is necessary to suppress the remaining active melanocytes.
Skin rejuvenation using intense pulsed light: a randomized controlled split-face trial with blinded response evaluation. [2006.08]
OBJECTIVE: To evaluate efficacy and adverse effects of intense pulsed light rejuvenation in a homogeneous group of patients... CONCLUSIONS: Three intense pulsed light treatments improved skin texture, telangiectasia, and irregular pigmentation but had no efficacy on rhytids. Adverse events were minimal, but included scar in 1 patient.
Split-face comparison of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone for photodamage. [2006.06]
CONCLUSION: Short-contact ALA-PDT-IPL brings about greater improvement in photodamaged skin and greater clearance of AK lesions than IPL alone, further confirming the usefulness of ALA-PDT in photorejuvenation.
Intense pulsed light treatment of 1,000 consecutive patients with facial vascular marks. [2006.03]
BACKGROUND: Facial teleangectasias or vascular marks often represent a very cosmetically detracting problem for the affected patient, who tries to cover the lesions by camouflage strategies. This study describes the response of these vascular lesions after an intense pulsed light source was used on 1,000 consecutive patients... CONCLUSION: The intense pulsed light source Photoderm VL can be considered a fast, safe, and effective treatment for facial teleangectasias or vascular marks.
Split treatment of photodamaged skin with KTP 532 nm laser with 10 mm handpiece versus IPL: a cheek-to-cheek comparison. [2006.02]
BACKGROUND AND OBJECTIVES: The treatment of photodamaged skin with potassium-titanyl-phosphate (KTP) laser and intense pulsed light (IPL) has been reported in several studies. Each device has strengths and weaknesses; however, patient and device variability have made it difficult to ascertain the optimal device for photorejuvenation. The objective of this study was to obtain a head-to-head comparison of IPL and KTP laser for photorejuvenation. Each patient received one KTP laser treatment on one side of the face and one IPL treatment on the other side... CONCLUSIONS: Both large spot KTP and IPL achieved marked improvement in vascular and pigmented lesions in one session. The KTP laser caused slightly more discomfort and edema than the IPL. On the other hand, the KTP laser was faster, and more ergonomically flexible. Copyright 2005 Wiley-Liss, Inc.
Ablative versus non-ablative treatment of perioral rhytides. A randomized controlled trial with long-term blinded clinical evaluations and non-invasive measurements. [2006.02]
BACKGROUND AND OBJECTIVE: To compare efficacy and side effects of CO(2) laser resurfacing and intense pulsed light (IPL) rejuvenation for treatment of perioral rhytides... CONCLUSION: CO(2) laser resurfacing induces a significantly higher degree of clinical rhytide reduction followed by considerably more side effects compared to IPL rejuvenation in a homogeneous group of patients. Copyright 2005 Wiley-Liss, Inc.
A side-by-side prospective study of intense pulsed light and Nd:YAG laser treatment for vascular lesions. [2006.02]
Recently, lasers and light systems are used more for the treatment of vascular lesions due to their noninvasiveness, ease of use, and short recovery time... Overall, satisfaction with treatment of vascular lesions was greater with Nd:Yag although this method was more painful.
Topical 5-aminolevulinic acid combined with intense pulsed light in the treatment of photoaging. [2005.10]
BACKGROUND: The adjunctive use of 5-aminolevulinic acid (5-ALA) with intense pulsed-light (IPL) treatments has been suggested to increase the benefit of IPL for photoaging; however, to our knowledge, no controlled trials have been performed... CONCLUSIONS: The adjunctive use of 5-ALA in the treatment of facial photoaging with IPL provides significantly greater improvement in global photodamage, mottled pigmentation, and fine lines than treatment with IPL alone, without a significant increase in adverse effects. This combination treatment enhances the results of photorejuvenation and improves patient satisfaction.
Ultrastructural changes seen after ALA-IPL photorejuvenation: a pilot study. [2005.03]
BACKGROUND: Intense pulse light (IPL) treatment currently represents one of the most popular non-ablative photodamage skin treatments. Recent anecdotal evidence suggests that aminolevulonic acid (ALA) photodynamic therapy using IPL as a light source is superior to IPL alone for photorejuvenation... CONCLUSION: This small pilot study is the first to focus on the ultrastructural changes seen after ALA-IPL photorejuvenation. We found a greater shift toward type I collagen synthesis in the ALA-IPL group compared to the IPL group. The addition of ALA to IPL treatment for photorejuvenation may be superior to IPL alone.
Enhanced full-face skin rejuvenation using synchronous intense pulsed optical and conducted bipolar radiofrequency energy (ELOS): introducing selective radiophotothermolysis. [2005.03]
BACKGROUND: The authors previously reported their experience achieving non-ablative skin enhancement with serial, full-face, intense pulsed light treatments in a large series of patients. A new method for skin renewal electro-optical synergy (ELOS), which combines intense pulsed optical energy and conducted bipolar radiofrequency (RF) energy into a single pulse, has been recently introduced. Intense pulsed optical energy and bipolar RF energy have been used in dermatologic surgery for many years; however, this study represents the therapeutic impact of the combined energies. OBJECTIVE: The authors report their experience using an ELOS system (Aurora SR, Syneron, Yokneam, Israel) on 108 consecutive patients treated with a series of full-face procedures... CONCLUSIONS: This study demonstrates the safety and efficacy of a new technology using combined optical and conducted bipolar RF energies for noninvasive skin rejuvenation. The results show improvement in wrinkle reduction and amelioration of erythema, telangiectasia, and hyperpigmentation comparable to that reported for other intense pulsed light technologies.
Photorejuvenation of facial skin with topical 20% 5-aminolevulinic acid and intense pulsed light treatment: a split-face comparison study. [2005.01]
BACKGROUND: Photorejuvenation of facial skin has been reported after intense pulsed light (IPL) therapy alone and in conjunction with topical 5-aminolevulinic acid (5-ALA), but no comparative studies between these regimens have been performed. OBJECTIVE: To evaluate the safety and effectiveness of combination topical 5-ALA and IPL compared to IPL treatment alone... CONCLUSIONS: Photodynamic therapy with combination topical 5-ALA + IPL is safe and more effective for facial rejuvenation than IPL treatment alone.
Using intense pulsed light for cosmetic purposes: our experience. [2004.05]
The authors' experience using intense pulsed light for skin rejuvenation is summarized and analyzed with regard to its efficacy, safety, and complications. Rejuvenation using intense pulsed light was performed on 59 patients over a 6-month period (January of 2002 to July of 2002); these patients served as the study group.
The effect of full-face broadband light treatments alone and in combination with bilateral crow's feet Botulinum toxin type A chemodenervation. [2004.03]
BACKGROUND: Broadband light (BBL; Intense Pulsed Light; Lumenis Ltd., Yokneam, Israel) is a powerful, nonablative, light-based technology that targets melanin and hemoglobin and stimulates the formation of collagen and elastin. Botulinum toxin type A (BTX-A; BOTOX; Allergan Inc., Irvine, CA) treatment of the lateral periocular region relaxes the vertical fibers of the orbicularis oculi and results in softening of the lateral orbital crow's feet rhytides and widening of the palpebral aperture. OBJECTIVE: To compare the effects of full-face BBL in combination with BTX-A and BBL alone in female subjects with Fitzpatrick I-III skin types, Glogau II-III rhytides, and significant associated facial lentigines and telangiectasia... CONCLUSIONS: The patients in this study benefited from both treatments. Although BBL led to a remarkable improvement in full-face telangiectasias, lentigines, and skin texture, the improvement increased in all categories with combination therapy. In addition, an added improvement in the full-face aesthetic with both BTX-A and BBL therapy combined was obvious. These results suggest that both treatments--although evidently complementary--may also act synergistically to produce optimal clinical effects, revolutionizing the treatment of facial aging.
Photorejuvenation with intense pulsed light: results of a multi-center study. [2004.01]
This multi-center study evaluating the role of Intense Pulsed Light (IPL) in the non-ablative rejuvenation of Type I and Type II photoaged skin study was conducted in order to evaluate the clinical efficacy and safety of using IPL in treating clinical indications associated with photoaged skin...
Effectiveness and safety of ALA-IPL in treating actinic keratoses and photodamage. [2004.01]
BACKGROUND: Photorejuvenation involves the use of a light source or laser in reversing the signs of aging. The Intense Pulsed Light (IPL) has demonstrated effectiveness in treating signs of photodamage. Photodynamic therapy is a relatively new and promising treatment for actinic keratoses. OBJECTIVE: To determine the effectiveness of ALA-IPL in treating actinic keratoses as well as reversing the signs of aging... CONCLUSIONS: ALA-IPL treatment is effective in treating both actinic keratoses and signs of photodamage. In this study, we achieved significant improvement after just one treatment. ALA-IPL is a safe, effective way to treat both actinic keratoses and photodamage with little down time.
Intense pulsed light source for the treatment of dye laser resistant port-wine stains. [2003.04]
OBJECTIVE: The purpose of this clinical study was to evaluate the efficacy of an intense pulsed light (IPL) irradiator system for the treatment of port-wine stains (PWS) resistant to multiple pulsed dye laser (PDL) treatments... CONCLUSIONS: Approximately half of a group of PWS patients, who did not respond to previous PDL treatments, obtained good or excellent clinical effect after four treatments with the IPL system. All PWS, except those located in the V2 area of the face, responded to the treatments.The IPL treatment modality was found to be safe and efficient for the treatment of PWS, except for those located in the V2 area.
Intense pulsed light technology and its improvement on skin aging from the patients' perspective using photorejuvenation parameters. [2003.02]
Intense pulsed light technology (IPL) has been used for photorejuvenation or the reversal of skin aging. There are few studies to address the putative benefits from the patients' perspective... This finding may be useful when discussing intense pulsed light technology with current patients and those prospective patients considering this procedure.
Non-ablative facial skin photorejuvenation with an intense pulsed light system and adjunctive epidermal care. [2003.01]
Laser skin resurfacing is popular, but the appearance of the face during healing is unpleasant. Non-ablative photorejuvenation with intense pulsed light (IPL) has been reported as being successful but with varied results... The good patient satisfaction obtained was clearly demonstrated in the histologies and evaluations throughout the study.
Laser and intense pulsed light therapy for the esthetic treatment of lower extremity veins. [2003.01]
The role of lasers and intense pulsed light sources has gained increasing popularity over the last decade. Major advances associated with improved results are the main reasons associated with this increasing popularity...
IPL technology: a review. [2003.01]
BACKGROUND AND OBJECTIVES: Intense pulsed light (IPL) systems are high-intensity light sources, which emit polychromatic light. Unlike laser systems, these flashlamps work with noncoherent light in a broad wavelength spectrum of 515-1,200 nm. These properties allow for great variability in selecting individual treatment parameters and adapting to different types of skin types and indications. The purpose of this article was to critically review international medical publications of the many indication in which IPL technology can be used, including our own evaluations and experiences... CONCLUSIONS: The distinctive technical conditions involved combine to make IPL technology an alternative and auxiliary treatment option to existing laser systems and conventional therapies. Copyright 2003 Wiley-Liss, Inc.
Rejuvenation of photoaged skin: 5 years results with intense pulsed light of the face, neck, and chest. [2002.12]
BACKGROUND: Photorejuvenation involves the use of lasers or light sources to reverse signs of photoaging. Multiple devices have been shown to be effective over the short-term. OBJECTIVE: To investigate the long-term clinical results on the face, neck and chest at 4 years using filtered flashlamp intense pulsed light (IPL) for treatment of photoaging changes of telangiectasias, dyspigmentation, and rough skin texture... CONCLUSION: Signs of photoaging including telangiectasias and mottled pigmentation of the face, neck, and chest, can be improved by IPL with a long-lasting result. Minimal or no downtime with minimal adverse effects can be achieved with the settings reported. Skin textural smoothing, although not easily quantified, is an additional benefit observed long-term.
Photodynamic photorejuvenation. [2002.08]
BACKGROUND: The visible signs of photodamage are characterized by wrinkling, coarse skin texture, pigmentation alterations, telangiectases, and in some case actinic keratosis (AKs). Intense pulsed light (IPL) photorejuvenation has been shown to improve each of the different components of photodamaged skin except AKs. OBJECTIVE: To present photodynamic therapy with topical 5-aminolevulinic acid (ALA-PDT) using IPL as a light source for treatment of AK in patients having IPL photorejuvenation... CONCLUSION: This study describes a new application of IPL technology. Patients who are candidates for photorejuvenation procedures presenting with AKs can now have AKs treated as part of the photorejuvenation process rather than necessitating separate topical therapy with 5-fluorouracil (5-FU) or cryotherapy. In addition, many patients with AKs may benefit from the combination treatment with 5-ALA and IPL.
Gross and microscopic findings in patients submitted to nonablative full-face resurfacing using intense pulsed light: a preliminary study. [2002.08]
BACKGROUND: Intense pulsed light (IPL) is a noncoherent, nonlaser, filtered flashlamp emitting a broadband visible light that has been shown to be effective in photoepilation, as well as in a number of vascular and pigmented lesions of the skin. Their efficacy has also been reported recently in the treatment of photodamaged facial skin. In the last condition, however, there are few studies showing the clinical and microscopic changes produced by IPL. OBJECTIVE: To assess the gross and microscopic changes that occur in photodamaged skin submitted to nonablative full-face resurfacing (NAFFR) using IPL... CONCLUSION: Facial photodamage was clinically and microscopically improved using IPL. Use of IPL as a rejuvenating method seems to be promising, with minimal side effects, a wide safety margin, and minimal downtime.
["Skin rejuvenation" by non-ablative laser and light systems. Literature research and overview] [2002.06]
Currently, ablative laser therapy (with CO2/Er:YAG lasers) and deep chemical peeling are effective and promising methods of skin rejuvenation. The induction of collagen synthesis was observed after peelings with trichloroacetic acid or phenol as well as after treatments with the CO2 laser.After critical review and assessment of current literature, we can say that in terms of their efficacy, non-ablative methods are not a comparable alternative to ablative skin resurfacing.
A side-by-side comparative study of 1064 nm Nd:YAG, 810 nm diode and 755 nm alexandrite lasers for treatment of 0.3-3 mm leg veins. [2002.03]
BACKGROUND: Laser and intense pulsed light device treatments of leg veins have generally yielded disappointing results. Use of longer wavelengths, longer pulse widths, and better cooling devices have recently sparked renewed interests in these methods. OBJECTIVE: To prospectively compare, side by side, a 3-msec cryogen spray-equipped 755 nm alexandrite, a sapphire window cooled super-long-pulse 810 nm diode, and a variable pulse width, cryogen spray-equipped 1064 nm Nd:YAG laser for the treatment of 0.3-3mm leg veins... CONCLUSION: The cryogen spray-equipped 1064 nm Nd:YAG laser was remarkably effective and safe for the treatment of 0.3-3 mm leg veins. The use of topical anesthesia may be needed for some patients. The super-long-pulse 810 nm diode laser gave unpredictable results. Additional refinements of fluence and pulse width could improve its performance. The 3-msec, 755 nm alexandrite laser at fluences of 60-70 J/cm2 and an 8 mm spot can be effective, but inflammatory response, purpura, and matting limit its usefulness. Longer pulse widths might decrease these problems. For leg vein treatment, the 1064 nm wavelength is very safe for type V skin, the 810 nm wavelength at super-long pulse widths of 400-1000 msec is very safe for type IV and marginal for type V skin, and the 755 nm wavelength is limited to nontanned type I-III skin.
Full-face photorejuvenation of photodamaged skin by intense pulsed light with integrated contact cooling: initial experiences in Asian patients. [2002.01]
BACKGROUND AND OBJECTIVES: For Asian skin, recent "non-ablative" skin rejuvenation techniques have become the focus of attention for darker complected patients. In our earlier research, we have shown that intense pulsed light (IPL) technology can be applied to Asian skin with a high degree of safety and efficacy. In this study, we performed full-face photorejuvenation using a new IPL device incorporating a 560 nm filter and integrated contact cooling system for the improvement of various symptoms associated with photoaging in Asian patients... CONCLUSION: Full-face photorejuvenation for Asian patients using this device is not only effective but is also associated with fewer post-treatment complications than other more invasive modalities. We conclude that IPL photorejuvenation can be the basis for safe and effective skin rejuvenation in Asian patients. Copyright 2002 Wiley-Liss, Inc.
Evaluation of the long pulsed high fluence alexandrite laser therapy of leg telangiectasia. [2002.01]
BACKGROUND AND OBJECTIVES: The treatment of larger leg veins with laser or intense pulsed light often shows varying degrees of success and inconsistent clinical response rates. Aim of this study was to evaluate the effectiveness and safety of the 755 nm long pulsed high fluence alexandrite laser in the treatment of larger leg veins... CONCLUSIONS: The long pulsed high fluence alexandrite laser is effective and safe in the treatment of leg veins 0.3-1.3 mm in diameter. Copyright 2002 Wiley-Liss, Inc.
Full-face photorejuvenation of photodamaged skin by intense pulsed light with integrated contact cooling: initial experiences in Asian patients. [2002]
BACKGROUND AND OBJECTIVES: For Asian skin, recent "non-ablative" skin rejuvenation techniques have become the focus of attention for darker complected patients. In our earlier research, we have shown that intense pulsed light (IPL) technology can be applied to Asian skin with a high degree of safety and efficacy. In this study, we performed full-face photorejuvenation using a new IPL device incorporating a 560 nm filter and integrated contact cooling system for the improvement of various symptoms associated with photoaging in Asian patients... CONCLUSION: Full-face photorejuvenation for Asian patients using this device is not only effective but is also associated with fewer post-treatment complications than other more invasive modalities. We conclude that IPL photorejuvenation can be the basis for safe and effective skin rejuvenation in Asian patients.
Effects of intense pulsed light on sun-damaged human skin, routine, and ultrastructural analysis. [2002]
BACKGROUND AND OBJECTIVE: New, non-ablative methods can be used in skin rejuvenation. Histologic analysis of non-ablative IPL effects on facial, sun-damaged skin... CONCLUSIONS: Under these conditions, IPL induces minimal morphologic changes in mildly sun-damaged skin. Some esthetic improvement may be secondary to clearing of Demodex organisms and reduction of associated lymphocytic infiltrate.
Intense pulsed light source for treatment of facial telangiectasias. [2001.12]
OBJECTIVE: The purpose of this clinical study was to evaluate the effectiveness of the first intense pulsed light source (IPL) with dual mode light filtering for treatment of facial telangiectasias, and to evaluate the incidence of adverse including purpura, pigmentation and scars... CONCLUSIONS: An IPL with dual mode filtering is efficient and safe for treatment of facial telangiectasias.
Photorejuvenation for Asian skin by intense pulsed light. [2001.07]
BACKGROUND: Dermabrasion and deep chemical peeling are used in the treatment of photoaged skin. These ablative procedures are effective enough to produce a certain improvement but have often caused postinflammatory hyperpigmentation among Asian patients. To avoid such adverse effects, a new, nonablative procedure has been sought. OBJECTIVE: To determine the effectiveness of photorejuvenation for Asian skin using intense pulsed light (IPL). The specific parameters used, improvement ratios, side-effects, and downtime required are also discussed... CONCLUSION: Photorejuvenation using IPL is a completely safe and effective procedure even for Asian skin. It will be increasingly used for skin rejuvenation in the future.
Intense pulsed light and Nd:YAG laser non-ablative treatment of facial rhytids. [2001.01]
BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate the efficacy and safety of the intense pulsed light source (IPL) and the Nd:YAG laser in the treatment of facial rhytids. Both systems can be used in a non-ablative manner and cause a dermal wound. This is thought to stimulate the production of new collagen without epidermal disruption. Non-ablative techniques eliminate the downtime that must be endured by patients treated with ablative methods such as the carbon dioxide and erbium lasers... CONCLUSIONS: Although both non-ablative treatment systems improved facial rhytids presumably by causing a non-specific dermal wound, the Nd:YAG laser was better tolerated and produced fewer side effects. Copyright 2001 Wiley-Liss, Inc.
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