Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin. [2006.07]
OBJECTIVE: To evaluate the role of skin care products that contain a copper tripeptide complex, glycyl-l-histidyl-l-lysine-Cu(2+) (GHK-Cu), in treating carbon dioxide (CO(2)) laser-resurfaced skin... CONCLUSIONS: Copper tripeptide complex (GHK-Cu) skin care products placed on CO(2) laser-resurfaced skin offered no significant reduction or resolution of posttreatment erythema. Objective evaluation found no significant improvement in wrinkles or overall skin quality. However, patient satisfaction was significantly higher for those who used GHK-Cu skin care products after CO(2) laser skin resurfacing.
Superficial erbium:YAG laser resurfacing of photodamaged skin. [2006.06]
BACKGROUND: Light chemical peels and microdermabrasion have enjoyed recent popularity for the treatment of mild photoaging. However, clinical improvement from these modalities is often minimal from both a patient's and physician's perspective. Erbium:YAG lasers have been effective in treating mild to moderate photoaging, but the need for either regional or general anesthesia, as well as the significant post-treatment recovery period has limited its use. OBJECTIVE: We sought to utilize a very low fluence approach to erbium:YAG laser resurfacing, with topical anesthesia, to ascertain its efficacy in treating mild to moderate photoaging... CONCLUSIONS: One pass of low fluence erbium:YAG resurfacing, under topical anesthesia, was effective for the treatment of mild to moderate photoaging.
Red light-emitting diode (LED) therapy accelerates wound healing post-blepharoplasty and periocular laser ablative resurfacing. [2006.04]
BACKGROUND AND AIMS: Blepharoplasties can be associated with sequelae-related patient downtime, often extended or reinforced by periocular laser ablative resurfacing. The present controlled study examined the effects of a new-generation LED phototherapy system on enhancing wound healing following such combination surgery... CONCLUSIONS: In this small series of 10 patients, red LED phototherapy after blepharoplasty and laser ablative resurfacing cut the time to resolution of side effects and the healing time by one-half to one-third compared with contralateral unirradiated controls. Further studies are warranted with larger populations to confirm these findings.
Laser skin resurfacing with a novel portable erbium:YAG laser. [2006.04]
BACKGROUND AND OBJECTIVE: The erbium:YAG laser is a popular modality for laser skin resurfacing (LSR). This study was performed to evaluate the safety and efficacy of a new portable Er:YAG laser in the treatment of photo-damaged skin... CONCLUSION: The technique of applying a tailored number of 5-6 J/cm2, 300 micros pulses of a new portable Er:YAG laser to small areas appears to be safe and effective. There was minimal discomfort and a high level of patient satisfaction after a relatively short recovery time.
Patient satisfaction and reported long-term therapeutic efficacy associated with 1,320 nm Nd:YAG laser treatment of acne scarring and photoaging. [2006.03]
BACKGROUND AND OBJECTIVE: Nonablative laser treatments have become increasingly used for the treatment of acne scarring and photoaging. While nonablative laser treatments are more convenient and relatively safer than ablative laser resurfacing, efficacy and patient satisfaction with the level of improvement of textural abnormalities in acne scarring and rhytids associated with photoaging needs further study... CONCLUSION: Nonablative treatment with the 1,320 nm Nd:YAG laser induced significant patient-reported improvement in both acne scarring and photoaging. The majority of patients reported satisfaction with the degree of improvement.
Ablative versus non-ablative treatment of perioral rhytides. A randomized controlled trial with long-term blinded clinical evaluations and non-invasive measurements. [2006.02]
BACKGROUND AND OBJECTIVE: To compare efficacy and side effects of CO(2) laser resurfacing and intense pulsed light (IPL) rejuvenation for treatment of perioral rhytides... CONCLUSION: CO(2) laser resurfacing induces a significantly higher degree of clinical rhytide reduction followed by considerably more side effects compared to IPL rejuvenation in a homogeneous group of patients. Copyright 2005 Wiley-Liss, Inc.
Alabaster skin after CO2 laser resurfacing: evidence for suppressed melanogenesis rather than just melanocyte destruction. [2006.01]
Hypopigmentation is a recognized side effect of CO2 laser resurfacing.
Carbon dioxide laser resurfacing with fast recovery. [2005.03]
ABTRACT: Long sun exposure, in addition to ozone layer damage, produces structural damase to the normal skin. Injury to the dermal collagen and elastic fiber results in facial wrinkles.
Single-pass carbon dioxide laser skin resurfacing combined with cold-air cooling: efficacy and patient satisfaction of a prospective side-by-side study. [2004.11]
BACKGROUND: Ablative skin resurfacing with carbon dioxide (CO(2)) and erbium:YAG lasers is still considered the gold standard for treating rhytides, photodamage, and acne scars. However, the prolonged downtime and undesired concomitant effects that are involved have sent dermatologists looking for less invasive nonablative laser techniques to rejuvenate skin. OBJECTIVE: To combine cold-air cooling with single-pass CO(2) laser skin resurfacing to generate as much benefit as possible while minimizing the spectrum of adverse effects... CONCLUSIONS: Given the clear decline in demand for invasive laser technologies, single-pass CO(2) laser skin resurfacing in conjunction with cold-air cooling is a worthwhile alternative both to conventional resurfacing and to conventional subsurfacing. The use of cold-air cooling not only minimizes intraoperative and postoperative adverse effects, it also contributes strongly to patient satisfaction.
Connective tissue remodeling induced by carbon dioxide laser resurfacing of photodamaged human skin. [2004.11]
OBJECTIVE: To quantitatively examine the dynamics of molecular alterations involved in dermal remodeling after carbon dioxide (CO(2)) laser resurfacing of photodamaged human skin... CONCLUSIONS: The biochemical changes seen after CO(2) laser resurfacing proceed through a well-organized and highly reproducible wound healing response that results in marked alterations in dermal structure. These quantitative changes may serve as a means for comparison as other therapeutic modalities meant to improve the appearance of photodamaged skin are evaluated.
Botulinum toxin type A gives adjunctive benefit to periorbital laser resurfacing. [2004.11]
OBJECTIVE: Periorbital aging and lines are a result of intrinsic skin aging, ultraviolet damage, and repetitive action of periorbital muscles. Rejuvenation of this area should therefore be optimized by combining treatments that approach the different causative factors... CONCLUSION: This study illustrates the benefits of a combined approach to treating periorbital skin aging.
[Complications of laser facial resurfacing] [2004.10]
Laser resurfacing is a burn of the superficial skin layers: it's a controlled burn in its depth, that can destroy epidermis and the dermis superficial part, but not deeper for avoiding healing complications. All complications and the normal postoperative follow-up can be explained by the fact that laser resurfacing is a burn of the dermis and epidermis, with the destruction, partial or total, of their components.
[Complications of the resurfacing laser: retrospective study of 749 patients] [2004.08]
BACKGROUND: Resurfacing laser is one of the alternative treatment for cutaneous facial rejuvenation. Results are mainly good to excellent, but complications do occur with variable frequency. OBJECTIVES: The purpose of this study was to identify and report the complications they occurred during eight years laser resurfacing and to study their possible avoidance. The author experiences are discussed in conjunction with a review of published reports... CONCLUSION: Although laser resurfacing is a safe and effective method of facial rejuvenation, the cosmetic surgeon must be aware of the various complications that may be encountered. Prompt recognition of complications and appropriate management provide the best opportunity for an acceptable aesthetic outcome.
Utilization of the 1320-nm Nd:YAG laser for the reduction of photoaging of the hands. [2004.08]
BACKGROUND: Nonablative laser resurfacing has been shown to improve the appearance photoaged skin. Clinical improvement has been associated with dermal collagen remodeling. OBJECTIVE: The objective was to determine the efficacy of a 1320-nm Nd:YAG laser for the treatment of photoaging hands... CONCLUSION: This case series demonstrates that the 1320-nm Nd:YAG laser with cryogen cooling can be effective for rejuvenation of photoaged hands.
Herpes simplex virus prophylaxis with famciclovir in patients undergoing aesthetic facial CO2 laser resurfacing. [2003.10]
Herpes simplex virus 1 (HSV-1) reactivation may occur in patients undergoing facial carbon dioxide (CO2) laser resurfacing and can delay healing and result in severe scarring. Prophylactic oral antiviral agents are administered routinely to patients undergoing laser resurfacing to prevent postoperative HSV-1 eruptions; however, dosage and duration of treatment vary in the literature...
Full-face laser resurfacing using a supplemented topical anesthesia protocol. [2003.10]
BACKGROUND: Laser resurfacing has become a popular modality for the treatment of photodamaged skin, rhytids, and acne scarring. In many cases, this procedure is performed under general anesthesia or intravenous sedation in conjunction with nerve blocks and local infiltration.Scarring was not observed.Conclusion A supplemented topical anesthesia protocol for full-face laser resurfacing is a safe and effective alternative to traditional anesthesia strategies.
A prospective survey of patient experiences after laser skin resurfacing: results from 2 1/2 years of follow-up. [2003.10]
BACKGROUND: Laser skin resurfacing (LSR) is a common cosmetic surgical procedure, yet there are no prospective long-term studies on patients' perceptions of their procedure. OBJECTIVE: To prospectively document patients' subjective experiences after LSR... CONCLUSIONS: Data on the evolution of patient perspective after LSR can improve patient preparation. This may help the surgeon and patient achieve shared, realistic expectations for the postoperative period and for long-term results.
Microresurfacing using the variable-pulse erbium:YAG laser: a comparison of the 0.5- and 4-ms pulse durations. [2003.06]
BACKGROUND: Laser resurfacing has become less popular because of its long recovery time, significant discomfort, and potential risks. Microsurfacing employs the use of single-pass erbium:YAG (Er:YAG) "mini peels," which may be performed serially. OBJECTIVE: The purpose of this study was to evaluate the efficacy and patient acceptance of microresurfacing Er:YAG peels in treating facial photodamage. The variable-pulse Er:YAG system was used and was allowed a comparison of the 0.5- and 4-ms pulse widths... CONCLUSION: Microresurfacing is an effective and well-tolerated procedure. Benefits include its tolerability under topical anesthesia, limited down time, and high patient satisfaction.
Single-pass CO2 laser skin resurfacing of light and dark skin: extended experience with 52 patients. [2003.04]
BACKGROUND: Multiple-pass carbon dioxide (CO2) laser skin resurfacing has been a favored treatment modality for photodamaged and acne-scarred skin over the past several years. Its association with numerous side effects and complications, particularly prolonged erythema and dyspigmentation, however, has dampened the initial enthusiasm reserved for its use. By reducing the laser-associated tissue ablation depth and degree of thermal necrosis, it is possible that the incidence of these side effects can also be reduced. PURPOSE: To evaluate the clinical efficacy and side effect profile of single-pass CO2 laser skin resurfacing in a large series of patients... CONCLUSIONS: Single-pass CO2 laser skin resurfacing can improve the appearance of fine rhytides, mild atrophic scars, and infraorbital hyperpigmentation in all skin types. The severity and duration of side effects and complications are reduced with this technique (compared with multiple-pass procedures)and may offer a possible solution to the problem of treating patients with darker complexions.
Side effects and complications of variable-pulsed erbium:yttrium-aluminum-garnet laser skin resurfacing: extended experience with 50 patients. [2003.04]
Recent advances in technology have provided laser surgeons with new options for cutaneous laser resurfacing... Although more postoperative erythema is seen after variable-pulsed erbium:YAG laser treatment than is usually produced with a short-pulsed erbium:YAG system, the side-effect profile and recovery period after variable-pulsed erbium:YAG laser skin resurfacing still are more favorable than after multiple-pass carbon dioxide laser skin resurfacing.
Facial rhytides--subsurfacing or resurfacing? A review. [2003]
CONCLUSIONS: After critical review and assessment of current literature on the treatment of rhytides, we have found that non-ablative methods do not appear to be a comparable alternative to ablative skin resurfacing in terms of their efficacy and side effects.
Achieving superior resurfacing results with the erbium:YAG laser. [2002.10]
Laser skin resurfacing has become increasingly popular... The erbium:YAG laser is capable of achieving superior resurfacing results, while offering many advantages to the patient, eg, reduced anesthetic requirements, shorter healing time, reduced erythema, less risk of pigmentary change, and more flexibility for resurfacing the skin off of the face.
Nonablative laser skin resurfacing using a 1540 nm erbium glass laser: a clinical and histologic analysis. [2002.09]
BACKGROUND: A variety of laser systems have recently become available that allow for selective dermal remodeling without disruption of the epidermal surface. Modest clinical improvement in mild to moderate photoinduced facial rhytides with minimal morbidity is typical of these nonablative lasers, providing a significant advantage over traditional ablative laser systems. OBJECTIVE: To determine the clinical and histologic effects of a novel 1540 nm erbium glass laser on facial rhytides... CONCLUSIONS: The nonablative 1540 nm erbium glass laser system with contact cooling produces gradual clinical and histologic improvement in mild to moderate facial rhytides with minimal risk of serious adverse sequelae.
Cervicoplasty and facial laser resurfacing: a paired technique for facial rejuvenation. [2002.06]
OBJECTIVE: A specific group of patients interested in facial rejuvenation was identified in a plastic surgery practice. These patients were primarily concerned with improving their neck contour and correcting their facial rhytides. To address those problems a one-stage paired technique was designed - cervicoplasty with full-face laser resurfacing... CONCLUSIONS: Combining cervicoplasty with full-face laser resurfacing is a safe, effective procedure that provides another option in the realm of facial rejuvenation.
Valacyclovir prophylaxis for herpes simplex virus infection or infection recurrence following laser skin resurfacing. [2002.04]
BACKGROUND: The CO2 laser for cutaneous resurfacing has been associated with the reactivation of herpes simplex virus (HSV), causing delayed reepithelialization and scarring. Antiviral agents appear to be effective in reducing reactivation, however, the optimal therapeutic regimen has yet to be clearly defined. OBJECTIVE: To assess the reactivation rates of HSV after CO2 laser resurfacing in patients who received prophylactic valacyclovir for either 10 or 14 days... CONCLUSION: These results support the use of valacyclovir in a 10- or 14-day regimen as a preventive agent against HSV outbreaks following facial laser resurfacing.
The effect of a mucopolysaccharide-cartilage complex healing ointment on Er:YAG laser resurfaced facial skin. [2002.04]
BACKGROUND: There are several types of dressings which may be utilized after facial laser resurfacing. Laser surgeons favoring the open type of dressing have used the Aquaphor original formula to reduce the loss of moisture from laser resurfaced skin. The objective of this study was to compare the effectiveness of a mucopolysaccharide-cartilage complex (MCC) containing healing ointment with the standard therapy of Aquaphor ointment in treating erythema, edema, and skin erosion caused by Er:YAG laser resurfacing of facial skin. OBJECTIVE: To compare healing time after Er:YAG laser resurfacing treated side-by-side with MCC as compared with Aquaphor... CONCLUSION: The results of our study demonstrate that MCC healing ointment may provide an advantage over the standard therapy of Aquaphor ointment in the treatment of edema, erosion, and erythema caused by laser resurfacing of facial skin. Mean daily severity scores were consistently lower and improvement tended to occur earlier with MCC healing ointment.
Non-ablative cutaneous remodeling with a 1.45 microm mid-infrared diode laser: phase I. [2002.03]
BACKGROUND: Presented here is phase I of a three-part study of non-ablative cutaneous remodeling with a 1.45 microm diode laser configured with a cryogen spray cooling device... CONCLUSION: The 1.45 microm diode laser is capable of targeting dermal collagen and stimulating fibrosis at depths where solar elastosis resides. Longer unopposed heating times corresponded to increased erythema, edema, and pain, which were typically mild and short-lived. Epidermal burns can result in pitted scars.
Histopathologic and morphometric evaluation of the skin abnormalities induced by erbium:YAG and carbon dioxide lasers in 10 patients. [2001.10]
In the 1960s, carbon dioxide (CO2) laser therapy started to be applied to eliminate wrinkles, actinic scars, and acne because of its capacity of induce intracellular water vaporization. However, recent studies have shown the efficacy of the erbium laser in removing delicate and moderate scars...
CO2 laser resurfacing of the face and neck. [2001.10]
Laser resurfacing with the short-pulsed, high-energy CO2 laser has been used to treat photodamaged skin and acne scars. Efficacy and safety have been demonstrated with this technique since 1992... This article details the author's experience with CO2 laser resurfacing and promotes the use of sequential CO2/Er:YAG laser resurfacing.
One-pass CO2 versus multiple-pass Er:YAG laser resurfacing in the treatment of rhytides: a comparison side-by-side study of pulsed CO2 and Er:YAG lasers. [2001.08]
BACKGROUND: The CO2 laser is normally described as an aggressive resurfacing tool, whereas the erbium:YAG laser has enjoyed a reputation as the ideal tool for superficial resurfacing. The implication from many studies is that the CO2 laser is incapable of "minimally invasive" resurfacing. OBJECTIVE: To compare a short-pulsed CO2 laser with an Er:YAG laser over a range of parameters intended to produce equivalent microscopic and clinical injuries... CONCLUSION: When CO2 and Er:YAG lasers are used in a manner such that there are equivalent immediate postoperative histologic results, equivalent healing and cosmetic improvement occurs. One can use CO2 laser with one pass to mimic a moderately aggressive Er:YAG laser treatment.
Controlled vaporization of the skin for the treatment of wrinkles. [2001.08]
Resurfacing with CO(2) or Er:YAG lasers is a frequent technique used to achieve skin rejuvenation. The Er:YAG has gained wide acceptance since it can reduce the morbidity associated with CO(2) resurfacing... Laser is a safe, valid alternative treatment for cutaneous aging but prudence, together with observation should continuously guide skin resurfacing.
Effect of botulinum toxin pretreatment on laser resurfacing results: a prospective, randomized, blinded trial. [2001.07]
BACKGROUND: Facial laser resurfacing and chemodenervation with botulinum toxin type A are used independently as means of nonsurgical facial rejuvenation. Recent reports in the literature have described combining these 2 therapies, claiming improved and longer-lasting laser resurfacing results. To date, no scientific investigation has been undertaken to prove or disprove this theory... CONCLUSIONS: Hyperdynamic facial lines, pretreated with botulinum toxin before laser resurfacing, heal in a smoother rhytid-diminished fashion. These results were clinically most significant in the crow's feet region. We recommend pretreatment of movement-associated rhytides with botulinum toxin before laser resurfacing. For optimum results, we further recommend continued maintenance therapy with botulinum toxin postoperatively.
Lower eyelid CO(2) laser rejuvenation: a randomized, prospective clinical study. [2001.03]
PURPOSE: The effect of transconjunctival blepharoplasty alone compared with transconjunctival blepharoplasty and CO(2) laser skin resurfacing on lower lid bulging and wrinkles was examined. DESIGN: Randomized clinical trial. PARTICIPANTS: Forty-four subjects, including 13 men and 31 women... CONCLUSIONS: Transconjunctival blepharoplasty and adjunctive CO(2) laser resurfacing represents an excellent alternative to transcutaneous lower blepharoplasty. The procedure addresses lower lid wrinkles, skin redundancy, and fat herniation without a scar and with little risk of lower lid retraction.
Laser resurfacing with a long pulse erbium:YAG laser compared to the 950 ms pulsed CO(2) laser. [2001.01]
BACKGROUND AND OBJECTIVE: Laser resurfacing with the 950 micros pulsed CO(2) laser is an effective treatment for photodamage and acne scarring; however, the potential for prolonged erythema and delayed re-epithelialization dissuade many patients from the procedure. With the use of erbium lasers alone, there is a decrease in the incidence and severity of these adverse sequelae; however, it is difficult to achieve the same degree of improvement as with the CO(2) laser because of the more superficial depth of resurfacing. Thus, new erbium lasers have been developed with longer pulse durations to deliver increased thermal effects to tissue. It is hypothesized that with the use of these lasers, diminished erythema and faster wound healing will be observed as well as enhanced clinical outcomes... CONCLUSION: The VP Er:YAG laser can achieve a similar degree of improvement as seen with short pulse CO(2) laser resurfacing with decreased thermal tissue effects and decreased risk for adverse sequelae. Copyright 2001 Wiley-Liss, Inc.
Resurfacing of photodamaged skin on the neck with an UltraPulse((R)) carbon dioxide laser. [2001]
CONCLUSIONS: Despite some obvious improvements, the risk of scarring and hypopigmentation with the tested parameters out-weighs the potential benefits. The lower part of the neck responded very differently from the upper part. Alternative strategies to achieve better results are discussed.
Laser facial resurfacing: patient survey of recovery and results. [2000.12]
OBJECTIVE: To determine patient satisfaction with the postoperative recovery period and surgical outcome after facial laser resurfacing... CONCLUSIONS: Laser resurfacing produced excellent results for fine rhytids, skin quality, and sun-damaged skin.Return to social and occupational activities may occur early in recovery with the use of camouflage make-up. Patient education and close follow-up are necessary in the postoperative period.
Effects of skin cleaning modes on the condition of collagen and elastin after laser resurfacing. [2000.12]
CONCLUSIONS: It is suggested that the abrasive action caused by the gauze adds to the existing stimulative inflammatory reaction following CO2 laser resurfacing, which augments the collagen and fibre compaction response in the tissue. Comparatively aggressive cleaning with damp gauze may therefore be preferable to other methods when performing laser resurfacing.
A controlled evaluation of dermabrasion versus CO2 laser resurfacing for the treatment of perioral wrinkles. [2000.11]
Facial skin treatments with laser resurfacing, dermabrasion, and chemical peels were responsible for a significant portion of the 2.7 million cosmetic procedures performed in 1998. Perioral wrinkles are a common problem for which plastic surgical consultation is obtained... Patients consider more than the objective skin changes from a resurfacing technique when making a recommendation to a friend.
Post-laser hypersensitivity and the atopic patient. [2000.07]
Laser resurfacing has become an extremely popular modality in the treatment of the aging face. Reported complications associated with carbon dioxide laser resurfacing are on the increase...
Laser skin resurfacing of the face with a combined CO2/Er:YAG laser. [2000.02]
BACKGROUND: A combined, dual-wavelength CO2/Er:YAG laser system having the ability to deliver both clean ablation of skin with the erbium wavelength and a simultaneous deeper penetrating subablative thermal pulse of CO2 was developed for full-face resurfacing. The CO2 component can be pulsed from 1 to 100 msec at a power of 1-10 W with the Er:YAG component pulsed at 350 microsec at 1.7 J/cm2 through either a computer pattern generator with 3 mm diameter spot size or through a noncollimated spot ranging from 0.2 to 8 mm in diameter. Our previous study using this laser on the neck using a 4-8 mm diameter spot with Er:YAG fluence at 1.7 J and the CO2 at 5 W with a 50 msec pulse at a frequency of 10 Hz showed a higher degree of overall patient satisfaction, as well as improvement in skin texture and skin color, compared to patients treated with an Er:YAG laser alone. OBJECTIVE: This study evaluated the CO2/Er:YAG laser treatment modality in facial resurfacing... CONCLUSION: The CO2/Er:YAG laser utilized with four passes at the above-mentioned parameters results in a similar degree of improvement as other forms of laser resurfacing with high-energy, short-pulsed CO2 lasers
Erbium:YAG laser resurfacing of the hands, arms, and neck. [1999.10]
BACKGROUND: Resurfacing procedures to improve photodamage, rhytides, and scars have been developed and refined over the last century. Laser resurfacing is a relatively new procedure in the resurfacing spectrum. It has been appreciated that resurfacing of nonfacial skin by dermabrasion, chemical peels, or carbon dioxide (CO2) laser carries an unacceptably high risk of scarring. More recently, the erbium:YAG (Er:YAG) laser has been developed and marketed for facial and nonfacial resurfacing. Specifically, manufacturers have promoted Er:YAG lasers as safe for resurfacing photodamaged skin on the hands, forearms, and neck. Surprisingly, there is little evidence to support these claims. OBJECTIVE: To evaluate the safety and efficacy of resurfacing photodamaged skin on the dorsum of the hands, forearms, and neck with an Er:YAG laser... CONCLUSION: Er:YAG laser resurfacing of the hands, forearms, and neck may be safely performed. Topical anesthesia alone is inadequate, healing takes up to 3 weeks, and cosmetic improvement is minimal with the parameters used in this study.
Cutaneous laser resurfacing. [1999.09]
Cutaneous resurfacing with the new generation of carbon dioxide and erbium lasers has recently come into favor for the treatment of facial rhytides, photodamage, and scarring. The precise control of these resurfacing lasers over the extent of tissue vaporization minimizes thermal damage to the skin while maximizing therapeutic efficacy...
Laser resurfacing: usual and unusual complications. [1999.05]
The use of the carbon dioxide laser for skin resurfacing was initially described in 1989. 1 Since that time, several reports have shown it to be highly effective in the treatment of photodamaged skin and acne scarring.
Long-term effectiveness and side effects of carbon dioxide laser resurfacing for photoaged facial skin. [1999.03]
CONCLUSION: Improvement from cutaneous laser resurfacing has persisted for an average 24-month postoperative period with a low incidence of side effects. Hypopigmentation is the most common long-term side effect and appears to be related to the degree of pre-existing photodamage as it contrasts with the newly healed undamaged skin.
Comparison of four carbon dioxide resurfacing lasers. A clinical and histopathologic evaluation. [1999.03]
BACKGROUND: Several high-energy, pulsed and scanned carbon dioxide (CO2) lasers are currently available for cutaneous resurfacing. Although each laser system adheres to the same basic principles of selective photothermolysis, there are significant differences between lasers with respect to tissue dwell time, energy output, and laser beam profile. These differences may result in variable clinical and histologic tissue effects. OBJECTIVE: The purpose of this study was to examine the in vivo clinical and histopathologic effects of four different high-energy, pulsed or scanned CO2 resurfacing lasers... CONCLUSIONS: Equivalent clinical results were observed using the FeatherTouch, NovaPulse, TruPulse, and UltraPulse CO2 lasers. While postoperative erythema intensity differed between laser systems, total duration of erythema was equivalent. The four lasers under study resulted in minimal residual thermal damage and stimulated new collagen formation within 6 months after treatment.
Combined laser resurfacing with the 950-microsec pulsed CO2 + Er:YAG lasers. [1999.03]
INTRODUCTION: Laser resurfacing with the 950 microsec pulsed CO2 laser has been proven to be efficacious in improving photodamaged skin and acne scarring. Unfortunately, prolonged erythema and delayed wound healing are common adverse sequelae, which require intensive patient education and intervention. These adverse effects may be due to the degree of nonspecific thermal damage present after resurfacing with the CO2 laser. Since erbium: YAG (Er:YAG) laser vaporization leaves far less thermal damage, it is hypothesized that its use after CO2 laser resurfacing will decrease the extent of nonspecific damage and result in improved wound healing... CONCLUSION: Treating a patient with the Er:YAG laser after treatment with the UPCO2 laser results in a decreased incidence of adverse sequelae without a noticeable difference in the degree of wrinkle improvement.
Prophylactic antibiotics in patients undergoing laser resurfacing of the skin. [1999.01]
BACKGROUND: Carbon dioxide (CO2) laser resurfacing produces a superficial second-degree burn that needs to be protected from bacterial and fungal infections. OBJECTIVE: We investigated the effects of various systemic and topical antimicrobial regimens... CONCLUSION: Post-CO2 resurfacing infections are not rare but can appear subtly and might only be noticeable in the second postoperative week. Prophylactic intranasal mupirocin is ineffective, but ciprofloxacin is effective in preventing infection with both gram-positive and gram-negative bacteria. Oral ketoconazole and fluconazole are effective in preventing yeast infections.
Clinical and histologic evaluation of six erbium:YAG lasers for cutaneous resurfacing. [1999.01]
BACKGROUND: Several erbium:YAG lasers are currently available for cutaneous laser resurfacing. Although different laser systems are purported to produce equivalent laser energies to produce similar laser-tissue interactions, no comparative clinical or histologic studies have been performed to objectively demonstrate their relative efficacies. OBJECTIVE: The purpose of the present study was to examine the in vivo clinical and histopathologic effects of six different erbium:YAG resurfacing lasers... CONCLUSIONS: Equivalent clinical and histologic results were seen after each of the six erbium:YAG lasers studied. Erbium:YAG laser resurfacing can be used to significantly improve mild cutaneous photodamage and atrophic scars.
Comparative clinical trial of 2 carbon dioxide resurfacing lasers with varying pulse durations. 100 microseconds vs 1 millisecond. [1998.10]
OBJECTIVES: To compare the clinical and histological effects of 2 carbon dioxide lasers with different pulse durations and to evaluate the effect of carbon dioxide laser pulse duration on postprocedure erythema, wound healing, and efficacy of wrinkle treatment... CONCLUSIONS: Compared with the longer pulse-duration carbon dioxide laser, the shorter pulse-duration carbon dioxide laser, used with higher energy and more passes, caused slightly less erythema while maintaining efficacy. The longer pulse-duration laser required lower energy and fewer number of passes to achieve an equivalent depth of ablation, level of residual thermal damage, and degree of efficacy. The shorter TruPulse allows for more superficial tissue damage per pass and therefore is best suited for situations requiring superficial or more controlled ablation. The longer UltraPulse achieves a desirable depth of tissue damage with fewer passes. The data did not support the long-term presence of tissue collagen shrinkage in the treated areas.
A side-by-side comparison of carbon dioxide resurfacing lasers for the treatment of rhytides. [1998.10]
BACKGROUND: The use of cutaneous resurfacing lasers to treat rhytides is widely accepted. Several carbon dioxide lasers, many using fundamentally different technologies, are available. OBJECTIVE: The purpose of this study was to compare the results obtained and side effects after treating rhytides with 3 different carbon dioxide resurfacing lasers... CONCLUSION: Our results suggest that operator technique and patient selection are more important factors than laser type with respect to outcome.
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